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Drugs that pose health risks such as carcinogenicity and teratogenicity are internationally classified as Hazardous Drugs (HDs), and proper handling is required for their safe use.Medical facilities handle many types of HD, including anticancer drugs, and occupational exposure control for medical personnel who can often come in contact with HDs in their daily work is an important issue for medical safety.
Exposure is possible from splashing, leakage from needle tips, volatilization of HDs, and other such situations.
HDs may leak during manual procedures such as priming and needle insertion in/removal from a vial.
It has been reported that the amount of exposure to HD is affected by technique, which varies according to how experienced a healthcare professional involved in preparation and administration might be.